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Body composition changes become noticeable at 4-6 weeks

Empagliflozin Effectively Lowers Liver Fat Content in Well-Controlled Type 2 Diabetes: A Randomized, Double-Blind, Phase 4, Placebo-Controlled Trial

Rosengren E, Rorsman H

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Different antioxidants have been reported to counteract DNA hypermethylation by multiple mechanisms, including epigenetic regulation and chromatin remodeling process [262]