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In the case of ALT, the relative amount of mitochondrial isoenzyme is small, and its plasma half-life is extremely short, making it of no diagnostic significance

M.& Yang, T

Oncol Rep 38(6):33193326

When two or more dimensions shift toward a pro-oxidative state, such as reduced DHODH activity due to POLQ or E2F4 inhibition, D-lactic acid accumulation triggered by CDK7-YAP-LDHD pathway disruption, or CD8 + IFN- silencing of SLC7A11, CSCs lose self-renewal capacity and become susceptible to ferroptosis

Base infusion consists of a half liter of 0.9 normal saline

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