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ICAM1, Intercellular Adhesion Molecule 1

In addition, knockdown of Hmga1 significantly reduced the expression of HK2 in tumor cells and sensitized them to cell death induced by TNF alone or TNF/CHX in a RIPK1 kinase-dependent manner (Supplementary Fig

Research by U.S

This approach is particularly beneficial in trials involving multiple treatment arms or stratified subgroups, where conventional fixed designs often prove too rigid or inefficient