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In one series of patients with 5-oxoproline associated anion gap metabolic acidosis, renal dysfunction accompanied the diagnosis in 3 out of 4 patients [16]

Therefore, solubilisation using a denaturant such as urea was required

131,132 The brain is particularly sensitive to OS due to numerous variables, including rapid oxidative energy metabolism (a process through which ROS, which are harmful molecules, are constantly produced), high levels of unsaturated fatty acids (which are vulnerable to lipid peroxidation), and relatively low intrinsic antioxidant capability

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Momento de administracin: Los protocolos de investigacin habituales administran las cpsulas en ayunas (30 minutos antes de la comida) o con una comida ligera