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2.1 Pathophysiology of Parkinsons disease 2.1.1 Mechanism of neurodegeneration PD is caused by the progressive degradation of dopaminergic nerve cells in the substantia nigra, a part of the brain that is essential for controlling movement (31)

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Although currently only a few clinical studies have been conducted on the relationship between GD and depression, evidence has been able to point out the strong correlation between GD and depression

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