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With this biotransformation, liver detoxification, a long-standing barrier in nanomedicine translation, can be turned into a bridge toward maximizing targeting and minimizing nanotoxicity

4.1 Leukocyte-derived ROS Leukocytes, or white blood cells, are an important component of the immune system and are often present in semen, particularly in response to infections or inflammatory conditions in the male reproductive tract (81, 82)