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In AC, where hypoxia and radioresistance are more prevalent, the same dosimetric improvement may provide additional biological benefit, although this remains to be directly demonstrated

PMID: 18623381

The cardioprotective effects of nano-curcumin against doxorubicin-induced cardiotoxicity: a systematic review

136 In addition, acquired astrocytopathies are prominent in hepatic encephalopathy (in which astrocytes lose their homoeostatic capabilities 137 ) and in neuromyelitis optica, in which the astrocyte protein, AQP4 is the subject of autoimmune attack, leading to dysfunction and death of astrocytes resulting in pronounced inflammation and degeneration of neural tissue

ROS are generated very early after reperfusion of ischemic tissue, resulting in oxidative stress that is major cause of cellular injury.8 During ischemia, the physiologic form of the Xanthine dehydrogenase is converted to the ROS-producing form Xanthine oxidase.41 On reoxygenation, Xanthine oxidase reacts with molecular oxygen to produce ROS

found that EGCG reduced A1-42-induced memory dysfunction by altering the secretion of -secretase, in addition to EGCG inhibiting A1-42-induced apoptosis (113)