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[10] Il farmaco in ultima analisi agisce come donatore di gruppi acetilici che, associati con il coenzima A, intervengono nel ciclo di Krebs: vengono cos influenzati sia il metabolismo degli acidi grassi sia quello dei glucidi

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PMID 26811632

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However, in heart failure, pathological cardiac structure and functional reconstruction are often accompanied by significant reshaping in energy generation and transfer reshaping, manifested as a significant decrease in the metabolic efficiency of fatty acids and carbohydrates for energy but an increase in ketone oxidation (Lopaschuk and Ussher, 2016