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Of these two, itraconazole has most promise as a pharmaceutical invention targeting NPC1, since it is already included in several clinical trials as an anti-cancer drug due to its ability to inhibit hedgehog pathway as well as due to its various anticancer activities including its ability to target multidrug resistance via ABC transporters [120]

Kempe S, Kestler H, Lasar A, Wirth T (2005) NF-kappaB controls the global pro-inflammatory response in endothelial cells: evidence for the regulation of a pro-atherogenic program

Additionally, a comparison of different modes of small peptide delivery by L

When aminoglycoside-induced hearing loss is identified, whether through serial ototoxicity monitoring, universal newborn hearing screening, or clinical suspicion prompted by developmental concerns, comprehensive audiological characterization should follow promptly

Pharmacogenetics of intravenous and oral busulfan in hematopoietic cell transplant recipients