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These recent developments, combined with our observation that complex II inhibition via the succinate dehydrogenase is a druggable and highly potent target for broad-spectrum antiviral inhibition, raise the possibility for the rapid establishment of novel broadly acting antiviral drugs

Cumene hydroperoxide concentration is also increased from 12 mM up to 60 mM so that lipid peroxidation is increased and GP activity therefore is limited only by GP levels in RBC membrane preparations

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These constructs were engineered using two strategically placed PreScission protease sites for efficient tag removal during protein purification to yield the proteins PgAFP-F-S or AfAFP-F-S

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