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Since B12 is found primarily in animal products, including meat, fish, dairy, and eggs, a substantial reduction in food intake can reduce B12 consumption below optimal levels, particularly for patients who were already borderline deficient before starting treatment or whose diets lean toward plant-based foods

Once someone begins treatment with either dietary or supplemental sources, it can take weeks to months to replenish their B12 levels and resolve any symptoms resulting from the deficiency

Abolhassani N, Leon J, Sheng Z, Oka S, Hamasaki H, Iwaki T, Nakabeppu Y (2017) Molecular pathophysiology of impaired glucose metabolism, mitochondrial dysfunction, and oxidative DNA damage in Alzheimers disease brain

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment"

Lee, J.Y

patients who have had inhalation treatments of acetylcysteine without incident may still react to subsequent inhalation with increased airways obstruction