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10.1021/acsnano.2c10830 37 GargM.JohriS.SagarS.MundhadaA.AgrawalA.RayP.et al (2021)

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These multifaceted disruptions often result in chronic, non-healing wounds with an elevated risk of infection and lower-limb amputation 8,9

In addition to TJs, interendothelial gap also features adherens junctions (AJs) and related proteins functioning as junctional complexes, which are involved in the maintenance of BBB permeability, cell adhesion and angiogenesis (24)