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Although drug biotransformation in vivo can occur by spontaneous, noncatalyzed chemical reactions, most transformations are catalyzed by specific cellular enzymes

Statistical analysis Mann-Whitney tests were used to compare the distribution of outcomes between the pairs of groups considered

Phase i - modification [edit] In phase I, a variety of enzymes acts to introduce reactive and polar groups into their substrates

Then he got back in the pool and someone else talked about campaigning