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Efficacy estimation of erythropoiesis-stimulating agents using erythropoietin-deficient anemic mice

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Biochemical effects of acetaldehyde on the brain have also been observed in vitro in cerebral cortical neurons and brain microsomal preparations (Lahti & Majchrowicz, 1969

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Importantly, the fusion proteins that remained bound to the immobilized receptor at the end of the dissociation phase, rapidly dissociated upon injection of a pH 7.4 buffer during the regeneration phase (Supplementary Fig

38 During aging, elevated mtDNA mutations and impaired protein homeostasis synergistically induce excessive reactive oxygen species (ROS) production, resulting in oxidative stress and mitochondrial autophagy impairment, eventually perpetuating a vicious cycle of mitochondrial dysfunction