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Limit What Reduces Glutathione Certain habits quickly deplete your bodys natural glutathione: Smoking & alcohol Junk foods high in sugar or oil Sleep deprivation Overexposure to sun and pollution Prioritize hydration, fruits, and balanced sleep to naturally maintain healthy levels

Once oxidized, glutathione can be reduced back by glutathione reductase, using NADPH as an electron donor

Regular Exercise Physical activity boosts your body's natural antioxidant defenses, including glutathione production

Reductive stress and mitochondrial dysfunction: the hidden link in chronic disease

Additionally, a randomized trial showed a benefit in disease-free survival in breast cancer patients receiving presurgical peritumoral injection of lidocaine, which is also a VGSC inhibitor (331)