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Cell 152 , 3950 (2013)

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Functions of other than BRD4 ET and MLL4 PHD2/3 domains in BRD4 and MLL3/4, such as acetyllysine binding activity of bromodomains of BRD4 18,19,20 and TET3- and H4K16ac-binding activities of MLL3/4 40,41,42,43 may also contribute

The maternal gut microbiome in pregnancy: implications for the developing immune system

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Here, we demonstrated consistent metabolic benefits of an oral, gut- and liver-restricted LXR inverse agonist, TLC-2716, in rodent, NHP and HLO models and, ultimately, in healthy human participants, supporting the potential of this approach for the treatment of cardiometabolic diseases