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The number of articles after applying these filters were recorded under Filters added. For each review (1a-b, 2a-b, 3a-d), results from all databases were consolidated, duplicates were removed, and abstracts were screened based on the respective inclusion and exclusion criteria

In mouse studies with diet-induced obesity, this led to real weight loss, smaller fat cells, less body fat, lower cholesterol, all without cutting food intake or causing obvious side effects

Test any new products on a small area before applying them to your whole face

New studies continue to explore cardiovascular benefits, effects on fatty liver disease, and potential applications beyond weight loss

Skin Sins: 15 Ways to Wreck Your SkinAvoid skin damage by shunning bad habits like tanning, popping pimples, exfoliating too much, poor diet, smoking, and using the wrong skincare products

The rationale traces back further, to Kraus and colleagues in 2014 ( Nature ), who knocked down NNMT genetically in mice and protected them from diet-induced obesity