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Our mechanistic investigations revealed that intracellular GSSG elevation sensitizes hepatocytes to TNF killing by inducing IKK--SSG formation, leading to suppressed NF-B activation

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Researchers must comply with all applicable institutional, state, and federal regulations governing the use of research chemicals

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These molecular-level studies of ASD etiology have concentrated on factors associated with inflammation, but they have not clearly identified the specific cell types responsible for the immune abnormalities associated in individuals with ASD

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