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The menopausal transition (or perimenopause) begins, on average, four years before the final menstrual period

coli : by using a straightforward methodology, this novel system increases protein production levels, promotes protein solubility and low cost purification, and helps for protein immunogenicity, in which the H tag facilitates a simple, rapid, and adjuvant-free production from gene to antibody (Costa et al., 2013c)

doi: 10.1080/1028415X.2025.2472773

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The relative standard deviation (RSD) was 11.2%, indicating a fine reproducibility of the method

Schultz et al., 2008 a very large cohort study that included thousands of Norwegian mothers and their children