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By 1951, further refining of thiopurines led to the creation of 6-mercaptopurine (6-MP) and 6-thioguanine (6-TG) which were subsequently used to treat children with acute leukemias who up until that point only had corticosteroids and methotrexate available as treatments

The images were collected by microscope (Olympus) and laser confocal (Zeiss, LSM800)

Ltoff, S., Audrain, B., Bernier, S

The immune system helps to protect our body against diseases caused by virus, bacteria and parasites by recognizing and responding to antigens, the substances that cause the immune system to produce antibodies against it

Folia Morphologica , 76 (2), 316318

Cabrera R, Baez M, Pereira HM, Caniuguir AS, Garratt RC, Babul J (2011) The crystal complex of phosphofructokinase-2 of Escherichia coli with fructose-6-phosphate: Kinetic and structural analysis of the allosteric atp inhibition