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Gut motility can be supported by: Drinking 1.5 to 2 litres of water and herbal teas per day Consuming soluble and insoluble fibre from vegetables, fruits and moderate amounts of wholegrains

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Specifically, mitochondrial TBC1D15 promotes the hydrolysis of Rab7 GTP at the MLCS, leading to untethering of these contacts (Wong et al., 2018) and subsequent release of Rab7 effector proteins from GTP-bound Rab7 and lysosomal membranes, thereby influencing lysosomal dynamics