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There are many variables involved in a treatment program with B12 injections

The need for a blood transfusion after shoulder replacement surgery is very low at less than 5% as reported in studies.8-10 My rate of blood transfusion is less than 1%

(2005) E2100: A randomized phase III trial of paclitaxel versus paclitaxel plus bevacizumab as first-line therapy for locally recurrent or metastatic breast cancer [abstract]

This trial demonstrated a mean decrease in B12 levels of 19%, with a number needed to harm of 13.8 over 4.3 years

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