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The enzyme NNMT normally changes nicotinamide, a form of vitamin B3, by using methyl groups, which lowers nicotinamide adenine dinucleotide (NAD+) levels

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Introduction Stroke, caused by a sudden interruption to the blood supply of the brain, has a wide range of detrimental consequences that have contributed to its recognition as the leading cause of disability and second most common cause of death worldwide

Hyperpigmentation Concerns Skin hyperpigmentation is generally triggered or exacerbated by diverse factors including hormonal changes, nutritional status, but the major actor is sun exposure [17, 19]