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Ebselen derivative 1 demonstrates significant protective effects against cisplatin (HY-17394)-induced hair cell (HC) damage both in vitro and in vivo , effectively reducing oxidative stress, apoptosis , and ferroptosis in hair cells

Iron Metabolism Disorder Under Traumatic Brain Injury Condition Studies have confirmed that iron homeostasis in the brain is disrupted after TBI (Figure 2)

Up-to-now, there are no biochemical or/and immunological markers of the clinical efficacy of these drugs

6-Gingerol (1-[4-hydroxy-3-methoxyphenyl]5-hydroxy-3-decanone) and zingerone (4-(4-hydroxy-3-methylphenyl) butan-2-one) (Fig

CDK9 inhibition blocks the initiation of PINK1-PRKN-mediated mitophagy by regulating the SIRT1-FOXO3-BNIP3 axis and enhances the therapeutic effects involving mitochondrial dysfunction in hepatocellular carcinoma

Panminerva medica, 53 (3 Suppl 1), 65-70