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GH and IGF-1 Treatment of Multiple Endocrine Deficiencies Endocrine disorders involving deficient or excessive production of the important growth-promoting hormones (GH, IGF-1, thyroid hormones, glucocorticoids, and sex steroids), can lead to abnormally short or tall stature

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If you're over forty and experiencing declining energy despite adequate sleep and nutrition, NAD+ depletion is likely playing a role