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Key Takeaways B12 deficiency can contribute to nerve-related pain and fatigue that may worsen joint discomfort perception

doi: 10.1016/j.ebiom.2019.01.056 [DOI] [PMC free article] [PubMed] [Google Scholar] 49.Calabr A, Accardi G, Aiello A, Caruso C, Galimberti D, Candore G

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268 The elevated NAD + levels concomitant with SIRT1 switches the NF-B-dependent transcription into the RelB-dependent transcription of the TNF- in endotoxin tolerant sepsis blood leukocytes