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Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity

In a series of experiments on humans and mice, the researchers found that L-carnitine is broken down by gut bacteria to produce trimethylamine-N-oxide (TMAO), which previous research has linked to heart and artery damage

L-carnitine may be beneficial for cats or dogs on vegan, vegetarian or restricted diets

PDH activity was assessed from 1 mM [1- 14 C] pyruvate in the presence or absence of 5mM L-carnitine and the 14 CO 2 released was quantified by scintillation counting

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More comprehensive studies are needed to investigate the long-term effects of these diets and interventions and to what extent they are useful in clinical practice