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CGRP, a potent vasodilator presents in both peripheral and central neurons, plays a crucial role in neurogenic inflammation and sensitization (30)

L-Carnitine and heart disease

Neurology 67 , 14111420 (2006)

But when ROS production outpaces your cell's antioxidant defences, a state called oxidative stress, the excess free radicals damage DNA, lipid membranes, and proteins within the oocyte. This damage accumulates over decades of dormancy, which is why it becomes more relevant as you get older

Because the body spews free radicals when it uses oxygen, the brain is awash in rogue molecules

Conversely, upregulation of SLC39A14 in hepatocyte-specific TFR knockout mice leads to ferroptosis due to excess iron, making them more prone to liver fibrosis