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Fully automated sample processing and analysis workflow for low-input proteome profiling

After stopping a CYP3A4 inducer, as the effects of the inducer decline, codeine plasma concentrations may increase, with subsequently greater metabolism by cytochrome CYP2D6, resulting in greater morphine levels [see CLINICAL PHARMACOLOGY], which could increase or prolong both the therapeutic effects and adverse reactions, and may cause serious respiratory depression

thus, it is crucial to orchestrate mitochondrialnuclear communication that ensures a precise transcriptional response by the UPR mt

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doi:10.2165/00126839-200203020-00001

Overexpression of GSTA1 or treatment with bicyclol significantly decreased the rate of TG synthesis compared to the control (Figure 6B)