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Despite this critical aspect, more nanoparticle-based therapeutics is expected to become available in the near future, with the goal to fulfill official guidelines approved by the international scientific and medical community (Hare et al., 2017

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These patients are often symptomatic yet are not suitable candidates for surgical intervention and have few-to-no durable therapeutic options, highlighting the critical need for effective therapies after the aforementioned ones have failed

In the study of d'Uscio et al