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10.1093/toxsci/kfx230 37 WeiM.GuX.LiH.ZhengZ.QiuZ.ShengY.et al (2023)

Mitochondrial abnormalities have also been associated with point mutations in Hsp70 chaperone that makes it aggregation prone, thereby, increasing iron and free-radical load 15,16,17

therefore, in vivo studies in SCD mice to demonstrate in more detail a physiological significance of the TSS pathway in alleviating oxidative and ferroptosis stress are warranted

oxidative stress in the pathobiology of ischemic stroke

We therefore tested whether these factors are also required for the unrestrained DNA synthesis observed in oncogene-expressing cells upon PARP inhibition