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Some studies demonstrated that GST gene polymorphism carries have a positive correlation with brain cancer, Alzheimers disease, and Parkinsons disease development risk [54]

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Some claim that ALC is more easily absorbed by the body and may affect the brain and nervous system differently

Risk factors for cortical, nuclear, and posterior subcapsular cataracts

The pharmacological rationale rests on the concentration-dependent bactericidal activity of aminoglycosides, whereby higher peak-to-MIC ratios enhance killing efficacy, combined with the saturable nature of aminoglycoside uptake into renal tubular and cochlear hair cells: prolonged drug-free intervals between doses may reduce cumulative intracellular drug loading and thereby the potential for organ toxicity ( Meta-analytic evidence consistently supports extended-interval dosing as at least equivalent to multiple daily dosing in efficacy and safety