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This key role of antioxidants on microbiota probably extends beyond the digestive tract, as the beneficial effect of butyrate has been suggested for other human microbial ecosystems, such as the skin 46 , the gut-brain axis 47 and atopic diseases 48

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Studies demonstrate that oxidative stress is a significant factor in the occurrence of numerous types of cardiovascular conditions, including atherosclerosis, myocardial infarction, hypoxia, hypertension, and atrial fibrillation