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Blockade of glucose reabsorption in tubular cells by tofogliflozin could exert beneficial effects on tubulointerstitial damage in diabetic nephropathy by directly preventing the glucotoxicity to proximal tubular cells

Together, these findings highlight the importance of ABCC1 status in predicting treatment outcomes, independently of HER2/ ERBB2

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Benoist CC, Kawas LH, Zhu M, et al.: The procognitive and synaptogenic effects of angiotensin IV-derived peptides are dependent on activation of the hepatocyte growth factor/c-met system