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New England Journal of Medicine 358 (14): 14541464

Excessive hydrogen sulfide may contribute to sulfur intolerance, diarrhea, migraine, sulfur-smelling stool, flatulence, bad breath, body odor, nausea, breathing problems, fatigue, poor memory, dizziness, and irritability

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AP-1, activator protein 1

These alterations suggest impaired mitochondrial bioenergetics, consistent with previous reports showing reduced mitochondrial activity and altered lipid metabolism in lipedema adipose tissue [57, 58]

For this discussion, we define an MSP as having non-canonical and/or D-amino acid residues as components, and a molecular weight of 1,000 or larger