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Acetate was also associated with worse echocardiographic outcome measures and elevated BNP, despite its previously hypothesized benefit in the prevention of hypertension and heart failure in certain animal models 49

Table 2: Evaluation of S-sulfocysteine sodium salt as a source of l-cysteine in chemically defined, neutral pH feeds for CHO fed-batch processes Cysteine Low stability of cysteine results from dimerization and precipitation of l-cystine at neutral pH and 25 C

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