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For example, if addition of GSH temporarily prevents a protein interaction that would be deleterious under conditions of oxidative stress

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The GSH/GSSG ratio serves as a primary determinant of the cellular redox state, as reduced GSH is thought to repair oxidative damage to protein thiols and to support redox signaling, the regulation of cell proliferation, control of the cell cycle, initiation of apoptosis, modulation ofthe immune response, and maintenance of skin pigmentation

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Hooda Z, Ries S, Antonoff MB , Mehran R, Mitchell KG, Rajaram R, Rice D, Swisher S, Vaporciyan A, Walsh G, Hofstetter W

As expected, we detected decreased levels of p-p65 in ESCC samples treated with BSO (Figure 5a)