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30 , 31 Several preclinical studies have investigated the effect of high doses of vitamin C on challenging tumours such as glioblastoma multiform (GBM), breast cancer, colorectal cancer, mesothelioma and pancreatic cancer and showed promising results on the anticancer effect of vitamin C through hampering the tumour progression and tumour metastasis

doi: 10.1074/jbc.M205670200

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The morphology and coreshell structure of nanoparticles was examined by transmission electron microscopy