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Rajpathak S., Ma J., Manson J., Willett W.C., Hu F.B

In the UPS, proteins are selectively marked by ubiquitination, the covalent addition of ubiquitin (Ub) molecules to lysine residues, which signals and targets the protein for proteolytic degradation by the 26S proteasome

10.1016/j.bbrc.2004.02.158 Biochem Biophys Res Commun

Researchers interested in the peptide usually come to it for one of three questions: anxiety without sedation, cognitive performance under stress, or interferon-related immune modulation