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Mechanistic investigations suggest that these outcomes are driven by autoimmune responses, which result in the release of substantial concentrations of pro-inflammatory cytokines that injure the very tissue they were meant to protect

Cell Cycle (2013) 12(19):317583

Some particularly cautious protocols extend initial phases to 4-6 weeks, especially in patients with medical complexity or those extremely concerned about side effects

An ALT flare greater than 40 IU/L at delivery serves as an independent predictor of HBeAg clearance

These findings establish -syn as a key regulator of neuronal ferroptosis and highlight ether-PLs as potential therapeutic targets in synucleinopathies (Mahoney-Sanchez et al., 2022)

Research suggests that long-term or frequent use may have unintended effects on key biological processes, including antioxidant balance