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if the outer annulus fibrosus subsequently ruptures, the nucleus pulposus completely extrudes (non-contained herniation), potentially protruding into the spinal canal or lateral recess, compressing the cauda equina and nerve roots, causing pain or motor dysfunction (Figure 1)

Clinical use of BuTDS in urological field

The NAC region, enriched in hydrophobic residues, possesses strong amyloidogenic properties and serves as the principal driver of -synuclein aggregation 44

It is also effective for treating gum abscesses, dry throat, fever, and for washing jaundice [58]

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10.1016/s0022-1759(00)00321-5 69 ClmentV.RoyV.ParB.GouletC