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In the NMDA-induced olfactory bulbs (OB) excitotoxicity model, the expression of SIRT1 and SIRT4 in OB increased, while the expression of SIRT2 did not increase, which may be related to the recovery of olfactory function [123]

"There is clear historical evidence for its use by the Babylonians 4,500 years ago and by the Chinese 2,000 years ago." Researchers have found references to garlic in both Egyptian and Indian cultures dating back some 5,000 years

CQ: Validation, Writing review and editing

platensis in hemiparkinsonian rats arises through the downregulation of brain inflammatory-related enzymes and glial fibrillary acidic protein It protect against aluminium chloride-induced neural degeneration

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demonstrated that, in macrophages, BMAL1 modulated the mRNA expression of Nrf2 via direct E-box binding to its promoter and that its deletion disrupted Nrf2 activity and, consequently, stimulated the production of ROS and proinflammatory cytokines, such as IL-1