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Description

Lancet (2015) 385:95665

The primary pathological hallmark of PD is the presence of Lewy bodies, which are intracellular aggregates of the protein alpha-synuclein

Notably, patients with KRAS G13D and HER2 high had lower overall survival (OS) compared to those with KRAS G13D and HER2 low (HR = 3.769

While these findings support the hypothesis that restoring BAmicrobiota interactions could influence AD symptoms, causal evidence in humans remains limited and warrants further investigation