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Description

These different cleavages are carried out by proteases, including a disintegrin and metalloproteinase (ADAM10 and ADAM 17), mainly responsible for -cut cleavage in kidney cells (97)

Uric acid, fetal bovine serum (FBS), penicillin-streptomycin, HEPES, elastase, collagenase, cytochrome c, superoxide dismutase (SOD) and bovine serum albumin (BSA) were purchased from Sigma-Aldrich (Merck KGaA)

and 16 studies reported metabolic resistance and/or changes in efflux pump expression

doi: 10.1172/JCI2908 68 HindmarshPCDennisonEPincusSMCooperCFallCHDMatthewsDRet al

Furthermore, the behavioral attenuation of cocaine actions appeared together with NAC-induced restoration of the x c system, GLT-1, and AMPA/NMDA ratio in accumbal or striatal brain regions [8, 21, 57, 58]