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A previous study investigated the expression of various genes correlated with cell death cascades and suggested that the expression of the proapoptotic protein Bax- was increased in the hippocampus of AD patients, whereas the expression of the antiapoptotic protein Bcl-2 was not altered

Besides smooth muscles contraction, ADRA1A also involved in gluconeogenesis and glycogenolysis of adipose tissues in the liver

Defective mitophagy and the etiopathogenesis of Alzheimers disease

10.1016/j.ejogrb.2014.10.041 159

10.1038/nature01681

Under physiological conditions, GSH quenches oxidizing substances (such as reactive hydroxyl free radicals, peroxynitrite, and H 2 O 2 ) directly or reduces hydrogen peroxide (or lipid peroxide (lipid-OOH)) to water (or the corresponding lipid alcohol (lipid-OH)) under the catalysis of GPX (summarized in Fig