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IGF-1 in the liver can be transferred by insulin-like growth factor binding proteins (IGFBPs) to muscles, where it binds its receptor on the surface of muscular cells, phosphorylates AKT and promotes muscular cell proliferation [14]

Thus, targeting oxidative stress is crucial for treating LL-IRI

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There was a randomized controlled trial a few years ago that randomized psychiatrists to either answer the question what would you do for yourself if you were depressed versus what should I do if Im depressedwhat would you do if you were me? Eighty percent of the psychiatrists said that they would put the patient on an antidepressant, but only 40% of psychiatrists said that they would put themselves on an antidepressant