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Genistein and cancer: current status, challenges, and future directions

A study (Wen et al., 2024) also showed that reducing the downregulation of the SIRT1/Nrf2/GPX4 pathway could increase the expression of SLC7A11 and inhibit ferroptosis in the hippocampus of splenectomized rats, thereby reducing the negative impact on cognitive function

612 In CRC cells, the expression of LSD1 can impair the TCF1 + PD-1 precursor cell subset of CD8+ T cells in the tumor microenvironment, thereby increasing the bodys resistance to PD-1 therapy

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