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A shared nearest neighbor (SNN) modularity optimization-based clustering algorithm and the Uniform Manifold Approximation and Projection (UMAP) algorithm were utilized to project all cells into two-dimensional coordinates for visualization

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Notably, the lower weight loss (-13.7%) observed in REDEFINE 2 among individuals with T2D suggests that the magnitude of benefit achieved with combined GLP-1 and amylin receptor agonism may depend on the underlying metabolic status, highlighting the need for a more nuanced understanding of the mechanisms governing treatment response [13]

Catalysis Science & Technology 9(11):29312944

Coronal sections (250 mm) were cut using the Leica VT1000S Vibratome and then incubated in oxygenated aCSF (3234 C) for at least 1 h before recordings

[DOI] [Google Scholar] 237.Jain R., Jordan N., Schild D., van Hullebusch E.D., Weiss S., Franzen C., Farges F., Hbner R., Lens P.N