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This was further substantiated by the observation that inhibiting heightened GJ function with a GJ inhibitor in mice effectively diminished APAP toxicity, which correlated with reduced levels of oxidative stress in hepatocytes

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Some of these GSTs are overexpressed in cancer cells 11, 12 , suggesting that tumors could be selectively vulnerable and be targeted with prodrugs activated by the overexpressed enzyme

doi: 10.1007/s11910-022-01229-z 185 MontalbanXArnoldDLWeberMSStaikovIPiasecka-StryczynskaKWillmerJet al

Your coordination diminishes, increasing the risk of accidents

doi: 10.1007/s11259-023-10265-0