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2016 PMC4880177 Zagotta, WN

HTRA1 from OVX rat osteoclasts causes detrimental effects on endplate chondrocytes through NF-B

Their results demonstrated that SOD supplementation significantly improved renal function by reducing serum creatinine and neutrophil gelatinase-associated lipocalin (NGAL) levels (Ismy et al., 2022)

Nevertheless, the plasma ketone concentrations in the adults are relatively delayed, which would delay the counteraction of ketones on pathological processes